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When we combine arthrocentesis treatment with infiltration with growth factors, we usually do so with local anesthesia and mild intravenous sedation. In any case, the procedure is an outpatient procedure and the advantage of doing it with sedation is that it improves the patients comfort and their perception of the procedure. In any case, if a patient wishes to do it with local anesthesia, there is no technical problem in doing it with pure local anesthesia.