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70; 0. 57 to 0. 85; p0. 001; 0. 70 0. 50 to 0. 99; roflazin 0. 002; and 0. 46 0. 24 to 0. 86; p 0. 01, respectively. Analysis of 280 individuals with AF and a BPHV showed similar results with NOAC and warfarin. According to the review, there is evidence to support the use of traditional treatments such as antispasmodics, antidepressants and dietary modification in IBS. New therapeutic agents such as linaclotide, lubiprostone, plecanatide, rifaxamine and eluxadoline are more effective than placebo in treating symptoms, with tenapanor being a promising new agent. However, most patients receiving these medications remain symptomatic. Furthermore, widespread use of these drugs is not appropriate for all patients. According to specialists in Plastic, Aesthetic and Reconstructive Surgery, breast implants are the safest procedure with the most predictable result among the current options for breast augmentation surgery.

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