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Marco. Interleukin 36 IL-36 is a protein that is part of a large family of cytokines, has been recently discovered and is emerging as a relevant mediator for inflammatory disease. Specifically, the IL-36 subfamily consists of three ligands IL-36О, IL-36О, and IL-36О- and the natural IL-36 receptor antagonist IL-36Ra. Currently, it is known that these cytokines exert their effects through a specific receptor, consisting of the IL-36R and IL-1RAcP chains. Furthermore, IL-36 can promote innate and adaptive immune responses, acting on parenchymal and stromal tissue and a subset of specific immune cells. The three MSF clinics located in the Gaza Strip are now open and a surgical team is working in Al-Shifa hospital, while a transportable hospital is being set up to accommodate patients in need of recovery.
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