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Professors at DuPont Hospital for Children, in Wilmington, United States, investigated through chart review whether children undergoing tonsillectomy had a higher risk of weight gain and obesity. The study included 200 boys between 2 and 12 years old undergoing surgery and 200 controls matched by age and gender. All had a preoperative and postoperative body mass index BMI recorded 6 to 18 months later. The main outcome measure was BMI percentile BMI for age between groups. The Wilcoxon test was used to analyze the BMI before and after the surgical procedure and the Mann-Whitney test to compare the percentiles. Risk R compared overweight в 85 and obesity в 95 of patients before and after surgery. A correlation analysis examined the relationship between age and weight gain. Critically ill individuals on mechanical ventilation receive sedative and analgesic medications intravenously to reduce anxiety and promote ventilatory comfort and synchrony. These medications are often administered in high doses for long periods and are often associated with adverse effects such as bradycardia, hypotension, impaired intestinal motility, immobility, weakness, and delirium.

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