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immunized. Changes in antibody titers were not associated with the time between vaccination and surgery, age or weight at surgery, nor with blood products administered, number of previous doses, time in the BCP or diagnosis of heterotaxy for the most vaccines. 358 data sets were identified that contributed information to the analysis, representing a total of 56,044 adults in 63 countries. Pretreatment NNRTI resistance prevalence estimates in 2016 were 11. 0 7. 5 - 15. 9 in Southern Africa, 10. 1 5. 1 - 19. 4 in Eastern Africa, 7. 2 2.