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To this end, a seven-day actigraphic recording was carried out in 3,974 participants age 45. 8 В 4. 3 years; 62. 6 men of the PESA Progression of Early Subclinical Atherosclerosis study. Four groups were defined very short sleep duration 6 h; short, that is, 6 to 7 hours; reference, 7 a. to 8 a. ; and extensive, 8 h. The sleep fragmentation index was defined as the sum of the movement index and the fragmentation index. Finally, carotid and femoral three-dimensional vascular ultrasound and cardiac computed tomography were performed to quantify noncoronary atherosclerosis and coronary calcification. The relationship between mental health and microbial metabolism of species that colonize the gastrointestinal tract is one of the most intriguing and controversial topics in microbiological research.

Bidirectional gut microbiota-brain communication has been explored mainly in animal models, while in humans it has been relegated. Large-scale metagenomics studies could facilitate the translational process, but their interpretation is hampered by the lack of reference databases and tools to analyze microbial neuroactive potential. Compared to unvaccinated patients, immunized patients over 65 years of age have a lower probability of being admitted to the ICU and dying from complications associated with influenza.

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