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Calcium imaging experiments were performed to evaluate the responses of enteric neurons to tryptamine-evoked endogenous 5-HT release. Total GI transit, gastric emptying, small intestinal transit, and colorectal propulsive motility were measured in live mice. To measure colonic migrating motor complexes CMMCs, these structures were physma and spatiotemporal maps were constructed along the proximo-distal length to quantify frequency, velocity, and length of CMMCs. Finally, villus height, crypt perimeter, and relative densities of enterochromaffin and enteroendocrine cells were measured in small intestine tissue. Through a meta-analysis of prospective cohort studies, the purpose of this research was to examine the relationship between the length of working hours and the incidence of cerebrovascular accident CVA and coronary heart disease. Mika KivimГki and collaborators identified studies through systematic reviews of PubMed and Embase, from their inception until August 2014.
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