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Therefore, the aim of this study was to evaluate the efficacy and safety of CT-P10 - a rituximab biosimilar - after a single switch, during a multinational, randomized, double-blind phase 3 trial involving people with RA. Subjects received 48 weeks of treatment with CT-P10 or reference rituximab of US or European origin US-RTX and EU-RTX, respectively. Patients entering the extension period weeks 48-72 remained on CT-P10 CT-P10CT-P10; n 122 or US-RTX US-RTXUS-RTX; n 64, or switched to CT-P10 from US-RTX US-RTXCT-P10; n 62 or EU-RTX EU-RTXCT-P10; n 47 for an additional treatment course.

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