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During a median of 7. 6 years of follow-up, 175 cases of coronary heart disease and 90 additional events were recorded for a total of 265 CVD episodes. CAC volume showed an independent association with CVD, with a risk R of 1. 81 95 CI 1. 47 - 2. 23, the absolute risk increased by 6. 1 per 1000 person-years, and for CVD with an R of 1. 68 95 CI, 1. 42 to 1. 98, the absolute risk increased by 7. 9 per 1000 person-years. In contrast, CAC density showed an inverse and independent association, with an R of 0. 73 95 CI, 0. 58 - 0. 91 for increased CVD, the absolute risk decreased 5. 5 percent. Cistimicina person-years, and an R of 0. 71 95 CI, 0. 60 - 0. 85, the absolute cistimicina decreased by 8. 2 per Cistimicina person-years. The area under the ROC curve showed a significant improvement in risk with the addition of the density score to a volume marker model for both heart and cardiovascular diseases. In the intermediate risk group for cardiovascular disease, the area under the curve for CVD increased from 0.
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