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This would avoid going through surgical solutions in adulthood. In the event that orthopedic intervention is not necessary, the orthodontist will monitor growth and tooth replacement every six months until the child has grown permanent teeth. Of the 1,303 infants enrolled in the Enquiring About Tolerance study, information was obtained from 1,225 94 of them through a standardized questionnaire on sleep at three years 618 GIS 95 and 607 GIT 93. Randomization was effective and there were no significant baseline differences between the two groups. After the early introduction of solids, newborns in the GIT slept much longer and woke up much less frequently than the GIS infants. The differences between both groups reached their maximum at the age of 6 months. At this time, in the intention-to-treat analysis, the GIT infants were sleeping 16.

6 95 CI 7. 8 to 25. 4 minutes more per night and their night-wake frequency had decreased from 2. 01 to 1. 74 watches per night. Clinically relevant very severe sleep problems that were significantly associated with maternal quality of life were reported significantly more frequently in the GIS odds ratio, OR, 1. 8; 95 CI, 1.