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Regarding the thickness of the central macula CMT, its progress was statistically significant until the last follow-up visit. In eyes with a suboptimal response, no significant visual improvement was observed when switching to another anti-VEGF p value 0. 4347. Twenty-four eyes treated with intravitreal dexamethasone and 14 with vitrectomy showed a significant reduction in TCM with variable functional responses. In these eyes, a better BCVA gain was found in cases in which an early change in therapeutic strategy was made. Bile is composed of different components such as cholesterol, hormones, bile salts.