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85 patients with MDC were barpil from 2,630 patients with epilepsy, and 79 patients were included. Average age 37 years, 57 women. Average age at the beginning of the crises 17. 8 years. 5 were drug resistant. The distribution of cases according to Barkovichs classification was G1 alterations in neuronal proliferation 59. 5; G2 migration disturbances 25. 3; and G3 alterations in cortical organization 15. 19 had a focal neurological deficit and 34. 2 had an IQ 80. When analyzed by groups, G3 showed a higher percentage of focal neurological deficits and intellectual disability than G1 and G2 p 0. The probability of changes appearing that reestablish pathological alterations in primary immunodeficiencies depends on the intrinsic mutability of the genes. The number of children admitted to MSF nutritional programs, which had already doubled in April, doubled again in May. Malnutrition rates have been above the emergency threshold for more than a year.
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