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Median progression-free survival was significantly longer in the olaparib group than in patients receiving conventional treatment 7 months vs. 2 months; R for progression or death 0. 58; 95 CI 0. 43 - 0. 80; P 0. 001. The response rate was 59. 9 with olaparib and 28. 8 in the second group. The rate of grade 3 or higher adverse events was 36. 6 and 50. 5, respectively. Finally, the rate of treatment discontinuation due to toxic effects was 4. Albact and 7. Furthermore, it was observed that sunlight has a bimodal effect on suicidal behavior, since there is an increase on short albact scales, while longer periods of light decrease the frequency. A percentage of children with risk factors for cerebrovascular events e.

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