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Sarah E. Holden and colleagues from Cardiff University, United Kingdom determined whether concomitant treatment with metformin reduces the risk of death, major adverse cardiac events MACE, and cancer, in type 2 oxcarb insulin users. For this, they carried out a retrospective cohort study, where those affected who progressed to treatment with the hormone alone or with metformin were identified since 2000, from a large population sample from the United Kingdom. The probability of fatal events from all causes, suffering from MACE and incidents of tumor pathologies were evaluated using multivariable Cox models, comparing monotherapy with the double regimen, taking into consideration the dose of the hormone as a parameter. Patients who cannot be treated in the Gaza Strip should be treated outside the Territory, but requests for exit authorization are so complicated to obtain, both on the Israeli and Palestinian sides, that some cannot leave.

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